Asthma inhaler. (Pixabay photo)

Lower childhood asthma rates from less prescribing of antibiotics: B.C. study

Children who were prescribed antibiotics as infants went on to develop asthma, study finds

Childhood asthma rates have fallen because fewer unnecessary antibiotics are being prescribed to babies within the first year of life, a study by British Columbia researchers says.

It says infants who were given antibiotics face nearly double the risk of asthma by age five. Earlier research shows the drugs affect so-called good bacteria in the gut.

Researchers from BC Children’s Hospital, the BC Centre for Disease Control and the University of British Columbia found that every 10 per cent increase in prescribing of antibiotics was linked with a 24-per-cent jump in asthma rates.

The study on the most common chronic childhood disease was published recently in The Lancet Respiratory Medicine.

Dr. David Patrick, first author of the study and director of research and medical lead of the antimicrobial resistance program at the BC Centre for Disease Control, said antibiotics should be prescribed only for serious infections.

“Most of those antibiotics were prescribed for conditions like viruses, colds, where there was no benefit,” said Patrick, who is also a professor with the school of population and public health at the University of British Columbia.

The findings involved analyzing the data of about 225,000 children up to age four in B.C., for every year between 2000 and 2015.

“This is the first time that we’ve demonstrated a population-level effect in any jurisdiction in the world where a reduction in antibiotic use in babies appears to be resulting in a drop in the asthma rate,” Patrick said.

The study also included the data of 2,644 children in Vancouver, Edmonton, Winnipeg and Toronto who are participants in the ongoing Canadian Healthy Infant Longitudinal Development cohort, or CHILD, which began in 2008 to study the development of various conditions from birth, including asthma, allergies and obesity.

Children who were prescribed antibiotics as infants and went on to develop asthma could potentially have the healthy bacteria replenished through further research, Patrick said.

Jacqueline Jones was randomly recruited to participate in CHILD at a hospital in Vancouver when she was pregnant with her daughter Charis, who is now nine.

She said her daughter was prescribed antibiotics for bronchitis when she was about nine months old and was diagnosed with asthma in March 2017.

Jones said it’s possible that the asthma is linked to the antibiotics, though she and her 15-year-old son Rhys also have asthma, which can run in families.

“Maybe it did increase her chances of having and developing asthma,” she said. “But at the time you have a not-even-one-year-old who’s coughing, having a hard time breathing and has this infection. When it’s a baby it’s quite scary.”

Jones said she’s hoping both her and her daughter’s participation in the CHILD study will one day lead to further advancements in the treatment of asthma.

Dr. Stuart Turvey, senior author of the study and a pediatric immunologist at BC Children’s Hospital, said that in 2000, about 70 per cent of children received at least one course of antibiotics before their first birthday but that had dropped by half by 2014.

“It was helpful to reduce antibiotic resistance in bacteria but now we see that it had unexpected benefits including being associated with a decreased rate of asthma in kids,” he said.

The CHILD cohort study involved the recruitment of about 3,000 pregnant women across the country to follow the health of their children over time.

Camille Bains, The Canadian Press

Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirus

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

RCMP bust five impaired drivers in one day in Terrace and Kitimat

Police were doing road checks as part of distracted driving, seatbelt enforcement campaign

Horgan makes campaign stop in Terrace and Kitimat

BC NDP leader met with local First Nations leaders, reiterated campaign promises

Unofficial holidays: Here’s what people are celebrating for the week of Sept. 27 to Oct. 3

World Farm Animals Day, Drink Beer Day and Virus Appreciation Day are all coming up this week

‘Monkey Beach’ supernatural film adaptation premiers at VIFF

Based on Kitamaat author Eden Robinson’s debut, mystical novel

COVID-19 cases grow to 13 at B.C. First Nation near Fort St. James

“This is very serious,” says Nak’azdli Whut’en Chief

Weekend sees 267 cases, 3 deaths in B.C.; Dr. Henry says events leading to COVID spread

There are currently 1,302 active cases in B.C., while 3,372 people are under public health monitoring

B.C. VOTES 2020: Echoes of HST in B.C. debate over sales tax

Cannabis, tobacco, luxury cars still taxed in B.C. Liberal plan

She warned her son about toxic drugs, then he was dead

Donna Bridgman’s son died at the age of 38 in Vancouver

B.C. food and beverage producers set record sales in 2019

Farmed salmon again leads international exports

Single vehicle rollover on Highway 16 claims life of young woman near Vanderhoof

The single vehicle incident occurred at Highway 16 and Hillcrest Way

Join Black Press Media and Do Some Good

Pay it Forward program supports local businesses in their community giving

B.C. marriage annulled because husband was unable to have sex with wife

Husband did not disclose any sexual health concerns to his wife prior to marriage

Most Read