A vial of a plant-derived COVID-19 vaccine candidate, developed by Medicago, is shown in Quebec City on Monday, July 13, 2020 as part of the company’s Phase 1 clinical trials in this handout photo. Medicago says it has received promising early test results for its plant-derived vaccine for COVID-19. THE CANADIAN PRESS/HO, Medicago

A vial of a plant-derived COVID-19 vaccine candidate, developed by Medicago, is shown in Quebec City on Monday, July 13, 2020 as part of the company’s Phase 1 clinical trials in this handout photo. Medicago says it has received promising early test results for its plant-derived vaccine for COVID-19. THE CANADIAN PRESS/HO, Medicago

Canadian company reports promising early Phase 1 test results of possible COVID-19 vaccine

Quebec City-based company says the side-effects were generally mild to moderate and short in duration

A Canadian biopharmaceutical company says it has received promising early test results for its plant-derived vaccine for COVID-19.

Privately held Medicago says interim results of a Phase 1 clinical trial found that 100 per cent of subjects developed an antibody response after two doses of its COVID-19 vaccine candidate.

“These are very promising results,” said Nathalie Landry, Medicago’s executive vice-president of scientific and medical affairs in a news release.

“We also observed that the antibody levels were higher after vaccination than those observed in convalescent sera from people who recovered from the disease.”

The Quebec City-based company says the side-effects were generally mild to moderate and short in duration.

The Phase 1 clinical trial was a randomized, partially blinded study of 180 healthy people.

Based on the Phase 1 data, Medicago plans to proceed with a Phase 2/3 clinical trial for its COVID-19 vaccine candidate, subject to regulatory approval.

The news comes a day after stock markets worldwide rallied on a report from Pfizer that a potential COVID-19 vaccine it’s developing with German partner BioNTech may be 90 per cent effective, based on early but incomplete test results.

“The positive results of our Phase 1 clinical trial are a step forward in the fight against the COVID-19 pandemic and we are confidently moving forward to our Phase 2/3 trial. We’re pleased that Medicago’s innovative manufacturing technology is helping to diversify the classes of COVID-19 vaccines candidates in development,” said CEO Dr. Bruce Clark.

The federal government has signed a deal with Medicago to secure the rights to buy 76 million doses of its vaccine.

VIDEO: Trudeau says he hopes to see COVID-19 vaccines roll out in Canada in early 2021

Medicago will also receive $173 million in funding from Ottawa for its vaccine research and development and for the construction of its Quebec City manufacturing facility.

Ottawa is also investing $18.2 million in a potential vaccine from British Columbia’s Precision NanoSystems and the National Research Council is to spend $23 million to support other Canadian vaccine initiatives.

Medicago was founded in 1999 and says its team includes over 450 scientific experts and employees in Canada and the United States, with academic affiliations in Europe and South Africa.

The Canadian Press


Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirusvaccines

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

The average selling price of a single-family home in Terrace has climbed 26 per cent in the last year. (Jonathan Hayward/The Canadian Press)
House prices soar in Terrace

Average prices increased by 26 per cent

Nurse Vicki Niemi administers a dose of the Pfizer-BioNTech COVID-19 vaccine to Joyce, 88, on Mar. 23, 2020 at the Terrace Sportsplex. All adults in Terrace are now eligible to register for a COVID-19 vaccination. (Ben Bogstie/Terrace Standard)
All adults in Terrace can now register for a COVID-19 vaccine appointment

Community members can register by calling 833-838-2323 or visiting getvaccinated.gov.bc.ca

April 2020 to March 2021 was the second wettest year on record since at least 1969, according to Environment Canada. (Ben Bogstie/Terrace Standard)
VIDEO: Terrace records wettest spell in over a half-century

Terrace saw close to 1,500 millimetres of precipitation between April 2020 and March 2021

Terrace fire department responded to a call from Skeena Saw Mills at the early hours of Friday morning. (Binny Paul/ Terrace Standard)
UPDATE: Fire crews respond to early morning incident at Skeena Sawmills

No injuries were reported as mill workers immediately alerted the fire department after seeing smoke

Terrace Tim Hortons on Keith Ave. experienced a fire during the morning of April 4, 2021. (Ben Bogstie/Terrace Standard)
Nature of Tim Hortons fire made it difficult to detect: Deputy fire chief

Fire likely burned undetected inside a wall, resulting in extensive damage

People take part in an anti-curfew protest in Montreal on Sunday April 11, 2021. Hundreds of people gathered in Old Montreal tonight in defiance of a new 8 p.m. curfew. THE CANADIAN PRESS/Giuseppe Valiante
VIDEO: Hundreds defy Montreal’s 8 p.m. curfew in violent, destructive protest

Quebec reported 1,535 new COVID-19 cases on Sunday, as well as five additional deaths linked to the virus

Dr. E. Kwok administers a COVID-19 vaccine to a recipient at a vaccination clinic run by Vancouver Coastal Health, in Richmond, B.C., Saturday, April 10, 2021. THE CANADIAN PRESS/Jonathan Hayward
B.C. to register people ages 40+ for COVID-19 vaccines in April

Appointments are currently being booked for people ages 66 and up

A volunteer disinfects a historical Mohabat Khan mosque ahead of the upcoming Muslim fasting month of Ramadan, in Peshawar, Pakistan, Friday, April 9, 2021. (AP Photo/Muhammad Sajjad)
For Canadian Muslims, second pandemic Ramadan is a time of hope and sadness

Many members of the association are trying to find ways ‘to help people stay connected to one another’

South Surrey farmland, March 2020. The province’s crackdown on secondary residences sparked protests that have the NDP government engaged in a lengthy rewrite of its legislation. (Tracy Holmes/Peace Arch News)
B.C. NDP now wants to keep even ‘non-farmers’ on the land

‘Grandfathering’ of second residences extended again

Photos of Vancouver Canucks players are pictured outside the closed box office of Rogers Arena in downtown Vancouver Thursday, April 8, 2021. The Vancouver Canucks say 25 players and coaches have tested positive during a COVID-19 outbreak that involves a variant of the virus. It is now the biggest reported outbreak in the NHL this season. THE CANADIAN PRESS/Jonathan Hayward
Canucks’ return to practice pushed back as player added to COVID protocol list

COVID outbreak has led to eight games being cancelled

People walk past the Olympic rings in Whistler, B.C., Friday, May 15, 2020. Whistler which is a travel destination for tourists around the world is seeing the effects of travel bans due to COVID-19. THE CANADIAN PRESS/Jonathan Hayward
Adults living, working in Whistler, B.C., eligible for COVID-19 vaccine on Monday

The move comes as the province deals with a rush of COVID-19 and variant cases in the community

RCMP crest. (Black Press Media files)
UPDATE: RCMP investigating after child, 6, dies at motel in Duncan, B.C.

The BC Coroners Service is conducting its own investigation into the circumstances around the child’s death

Most Read